I found out after my first mc that my little one had spina bifida. Folic acid given therapeutically enters the portal circulation largely unchanged, since it is a poor substrate for reduction by dihydrofolate reductases. Taking folic acid for at least one month before conception reduces the risk of neural-tube defects, such as spina bifida, by up to 70 percent, according to the Centers for Disease Control and Prevention. Folic acid or folate, which is referred to as the ‘pregnancy superhero’, should be consumed by women before and after they get pregnant. These effects may in part be responsible for the increased risk of miscarriage. This is really important in early pregnancy, and even before conception.Although I don't have any clotting disorders, I had to personally ask for the high dose folic acid from my GP, as I had done my research into it beforehand.In saying all the above, I don't know whether it has been the low dose aspirin, the high dose folic acid or the vitamin D deficiency being treated, but something worked and I am currently 22 weeks pregnant. I got our results back beginning December which came back clear, he advised to take low dose apirin! "That is extremely reassuring.". Folic acid supplements, multivitamins, and prenatal vitamins usually contain the recommended minimum amount of folic acid (at least 400 micrograms). You may have a higher risk if: you have diabetes; you or your partner have a neural tube defect; you have had a previous pregnancy affected by a neural tube defect Oct. 15, 2002 -- Taking folic acid before becoming pregnant is one of the best ways to prevent certain birth defects, and now research suggests it may also lower the risk of early miscarriage. I am still taking the vitamin D and aspirin, and will do until week 36. Evaluation of the impact of pharmacist polypharmacy reviews within the Govan Social … I've been finding it hard to get motivated with things after the miscarriage. I've read that if you have a high bmi higher than 30 you should be on a higher dose of folic acid does anyone know if this is true? The dose of folic acid recommended for women hoping to conceive is: folic acid 5mg daily . In 1998, the FDA began requiring food manufacturers to fortify certain grain products with folic acid. 1st time, 3rd time, 4th, 5th, 6th and then after 10 and 1/2 years of patience I had a beautiful baby boy, 100% healthy, no mental or physical problems. Also I'm aware I need to loose weight. The study, published this week in the Journal of the American Medical Association, was conducted by researchers from Sweden's Karolinka Institute in conjunction with the U.S. National Institute of Child Health and Human Services (NICHD). After having my daughter in 2009, I have since had 3 miscarriages and am now 7 weeks pregnant again. I did not take any, and had 5 miscarriages. MiL keeps taking money from DH - AIBU to say I never want to go see her again ?! I received my thrombophilia work up, the gynae said there was no problem, despite the fact that they were positive, as I was only hetero (for 3 different mutations). WebMD does not provide medical advice, diagnosis or treatment. Specializes in Family Medicine. Like you, all my tests came back clear for any problems. It sounds like you have been through it all!A prescription for folic acid is usually given when you have tested positive for the MTHFR mutation in the standard thrombophilia work up. It’s the synthetic form of folate.Folic acid is used by your body to make new cells and produce DNA. Researchers compared 468 women who had miscarriages between six and 12 weeks of their pregnancies with 921 women who were also in their first trimester, but had not miscarried. By clicking Subscribe, I agree to the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, Pregnant With Allergies? Top Treatment Tips, The D&C (Dilation and Curettage) Procedure. To comment on this thread you need to create a Mumsnet account. Folic acid/folate and vitamin B12 are both needed in the production of red blood cells and iron utilization. The recommended daily intake of folic acid for all women of childbearing age is at least 400 micrograms (mcg), or 0.4 milligrams (mg). This is page 1 of 1 (This thread has 3 messages.). Not sure about the whole folic acid thing. I was on folate with my first pregnancy but my doctor switched me to 5mg folic acid after my second miscarriage. Ju1es sorry for your losses and everything you have been through! Ovulation Tool: Find Your Most Fertile Days. After my fourth miscarriage I was prescribed 5mg folic acid which I started taking 3 months before I conceived again. Folic acid in its natural form is called folate. Some women will be advised to take a higher dose of 5 milligrams (5mg) of folic acid each day until they're 12 weeks pregnant if they have a higher chance of having a pregnancy affected by neural tube defects. This causes folate deficiency anaemia, which can cause tiredness and other symptoms. In fact Duphaston was given to prevent miscarriage. I had 4 consecutive miscarriages in a space of just over 1 year. Women who get at least 400 micrograms of the vitamin from their diets during the first few weeks of pregnancy can reduce their unborn baby's risk of neural tube defects (NTDs) by as much as 70%. In this article, MomJunction tells you all about folic acid during pregnancy: how much you need, how to obtain it (sources) and when to avoid taking it. It is still unbelievable, as I never thought I would have another baby again, but I am confident that the influx of one of the vitamins I increased in my diet helped this baby stick.Hope everything works out for you in the future. I'm taking normal vitamins in the morning but s I would ask my dr to explain their thinking behind prescribing aspirin and 5mg of folic - it is always useful to know - I know I want to know why. 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